WebJun 30, 2024 · NIH-funded study finds changes can affect food intake control circuitry and cause disorders to progress. June 30, 2024 • Press Release. Researchers have found that eating disorder behaviors, such as binge-eating, alter the brain’s reward response process and food intake control circuitry, which can reinforce these behaviors. WebA glucose-stimulated BOLD fMRI study of hypothalamic dysfunction in mice fed a high-fat and high-sucrose diet The hypothalamus is the central regulator of energy homeostasis. Hypothalamic neuronal circuits are disrupted upon overfeeding, and play a role in the development of metabolic disorders.
An Altered Pontine-Hypothalamic Functional Interplay Could …
WebAug 3, 2016 · Of note, the effect of exenatide on fMRI activity in the hypothalamus was opposite to that in other brain areas associated with the reward system. Obese individuals had a smaller hypothalamic fMRI signal in response to food cues than lean subjects, and exenatide infusion enhanced the hypothalamic fMRI signal. WebJan 2, 2012 · Qualitative analyses showed that MRI could also highlight finer structures such as the paraventricular nucleus, the ventromedial nucleus of the hypothalamus and … cth oder maxnom 50 % exw
Disrupted hypothalamic functional connectivity related to ... - LWW
WebOct 17, 2024 · Using behavioral phenotyping and resting-state functional magnetic resonance imaging (r-fMRI), we investigated the behavioral impact and cerebral alterations of chronic unpredictable mild stress (CUMS) in the rat. We also evaluated the efficacy of telmisartan therapy in this rodent model of depression. WebMar 3, 2024 · Traditional fMRI imaging measures changes to blood flow in the brain, as a proxy for neural activity. When neurons receive signals from other neurons, it triggers an … WebApr 21, 2024 · However, the investigation of in vivo hypothalamic responses to nutrient infusion using functional MRI (fMRI) is challenging. At present, the extent to which the hypothalamus as the core region for homeostatic regulation is involved in the pathophysiology of individuals with AN remains largely unknown ( 20 ). earthing system installation