Platinum ototoxicity

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August undefined, 2024

Webbof platinum (Pt) in industrial settings is respiratory sensitisation, often referred to as “platinum salt sensitivity” or PSS. • Not all forms of platinum are respiratory sensitisers. … WebbOnce severe ototoxicity has arisen, it is important to help with understanding of the spoken word, as this will greatly support a child’s development. The indication for hearing aids …

Understanding platinum-induced ototoxicity - ScienceDirect

Webb14 apr. 2024 · However, the development of ototoxicity is a serious hindrance of effective treatment. Although the mechanism for this toxicity has not been fully elucidated, it is accepted that the excessive production of reactive oxygen species (ROS) plays a major role in the development of platinum-induced hearing loss. WebbPlatinum-based therapy is the mainstay for management of high-risk neuroblastoma. Prevalence of platinum-related ototoxicity has ranged from 13% to 95% in previous … new testament cyprus

Understanding platinum-induced ototoxicity - ScienceDirect

WebbSelect search scope, currently: articles+ all catalog, articles, website, & more in one search; catalog books, media & more in the Stanford Libraries' collections; articles+ journal articles & other e-resources WebbPrescription drug information for thousands of brand, generic, and OTC medicines is available to registered members only. It's FREE to register and you'll have access to drug information and much more. WebbRESEARCH TRIANGLE PARK, N.C., Dec. 20, 2024 (GLOBE NEWSWIRE) -- Fennec Pharmaceuticals Inc. (NASDAQ:FENC; TSX: FRX), a specialty pharmaceutical company, following a pre-submission meeting with the oncology division of the U.S. Food and Drug Administration (FDA), has initiated a rolling New Drug Application (NDA) for … midway atoll henderson airfield

Sodium Thiosulfate and Risk of Ototoxic Effects From Platinum …

Platinum-Induced Ototoxicity in Children: A Consensus Review on ...

Webb16 nov. 2024 · Unfortunately, platinum-based therapies cause ototoxicity in many patients, and are particularly harmful to the survivors of pediatric cancer. Each year in the U.S. and … http://mdedge.ma1.medscape.com/fedprac/article/227870/oncology/improving-ototoxicity-monitoring-cisplatin-therapy-va-northeast-ohio new testament david bentley hartWebb8 okt. 2012 · Nedaplatin, a second generation platinum drug, is used to treat many of the same types of cancers as cisplatin. Nedaplatin is considered less nephrotoxic and … new testament dietary laws

"WebbImpact of Platinum-Related Hearing Loss on Quality of Life and Educational Attainment in Germ Cell Tumor Survivors CA210884 Jenny Poynter, Ph.D ... most common type of cancer in young adult men. After treatment for GCTs, patients may experience late effects such as ototoxicity (hearing loss), neuropathy, cardiac disease, second malignancies ... " - Platinum ototoxicity

Platinum ototoxicity

Clinical Evidence of Interaction between Nutraceutical …

Webb5 juli 2006 · Patients < 5 years at diagnosis had greater ototoxicity than older patients had, with adolescents/adults being the least affected. Findings were stable in repeated … WebbDrugs may cause hearing loss, dysequilibrium, and/or tinnitus. Common drugs include aminoglycosides, platinum-containing chemotherapy drugs, and high-dose salicylates. …

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Webb1 aug. 2013 · Ototoxicity, a platinum-associated side effect, receives renewed attention The US Food and Drug Administration (FDA) approved cisplatin in 1978 and carboplatin … Webb31 mars 2024 · Background: Platinum compounds are a group of fundamental chemotherapeutics used in the treatment of solid tumors, but they are burdened by side effects, such as ototoxicity. The objective of this study was to evaluate the incidence of ototoxicity caused by platinum compounds and [...] Read more.

WebbOur understanding of the role of cisplatin in ototoxicity is limited; however, research suggests that cisplatin uptake plays a crucial role. A recent study detected residual … Webb11 aug. 2024 · RESEARCH TRIANGLE PARK, NORTH CAROLINA-- (Marketwired - Aug 11, 2024) - Fennec Pharmaceuticals Inc. ( FRX.TO) ( FENCF ), a specialty pharmaceutical company focused on the development of Sodium...

WebbLate-onset hearing loss is known to occur long after cessation of cisplatin treatment, and these study results suggest that this delayed hearing loss may be related to long … Webb20 aug. 2024 · Platinum nanoparticles have also been used in the diagnosis of diseases [ 16, 17, 18 ]. Therefore, this review focuses on recent reports on the functionalization of platinum nanoparticles with bioactive molecules such as antibodies, biocompatible polymers, peptides, and biomolecules, among others, and their biomedical applications. 2.

WebbOtotoxicity (Concept Id: C0235280) Damage to the inner ear as a result of exposure to drugs or chemicals. Ototoxicity MedGen UID: 66719 •Concept ID: C0235280 Pathologic …

Webb17 maj 2024 · The main platinum compounds are cisplatin, carboplatin, and oxaliplatin. Their use in clinical practice has greatly improved long-term survival of pediatric … midway atoll tourismWebbPlatinum levels were inversely correlated with time since diagnosis (Figure; r= -0.39). We will measure the association between blood serum platinum levels and ototoxicity, while … midway atoll john c. waldronWebbCisplatin, carboplatin, nedaplatin, and oxaliplatin are widely used in contemporary oncology; however, their ototoxic and neurotoxic side effects are quite different as … new testament date of writingWebbPharmacogenomics of Cisplatin‐Induced Ototoxicity: Successes, Shortcomings, and Future Avenues of Research Clinical Pharmacology & Therapeutics Aug 2024 ... Copper (II) complexes of bidentate ligands exhibit potent anti-cancer activity regardless of platinum sensitivity status midway atoll wikipediaWebbAbout Cisplatin-Induced Ototoxicity. Cisplatin and other platinum compounds are essential chemotherapeutic agents for the treatment of many pediatric malignancies. Unfortunately, platinum-based therapies can cause ototoxicity, or hearing loss, which is permanent, irreversible, and particularly harmful to the survivors of pediatric cancer.ii midway attack dateWebbPlatinum-based chemotherapy-induced ototoxicity Samican Dabanlioglu tarafından 22 Ara 2024 "Are you listening to me?" Samican Dabanlioglu tarafından 18 Haz 2024. Faaliyet The March-April 2024 Issue:- Cancer Health Literacy in ... midway attack on japanese carriersWebb开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 new testament dating